Migraines are more than just headaches. They can cause nausea, sensitivity to light, and severe headaches that disrupt daily life. If you get migraines often, you’re probably looking for a natural way to feel better. Vitamin B2, or riboflavin, is a simple supplement that may help lower how often and how severe your migraines are.
This article explains how vitamin B2 can help with migraines, how to pick a good B2 supplement, and reviews the top choices for 2026. Whether you’re just starting out or want to improve your routine, you’ll find straightforward advice and product reviews here.
What is Vitamin B2 (Riboflavin) and How Can it Help with Migraines?
Vitamin B2, or riboflavin, helps your body turn food into energy. It also supports healthy skin, eyes, and nerves. For people with migraines, taking more riboflavin may help cut down on how often migraines happen and how bad they get.
How Riboflavin Helps with Migraines:
- Energy in Brain Cells: Riboflavin helps your brain cells make energy. People with migraines sometimes have trouble with this process, so getting enough riboflavin may help your brain work better.
- Lowering Inflammation: Riboflavin can help reduce inflammation in the body, which may play a role in migraines.
- Better Blood Flow: Riboflavin helps your body process certain amino acids, which can support healthy blood flow and may help prevent migraines linked to blood vessel problems.
- Fewer Attacks: Taking 400 mg of riboflavin each day may help prevent migraines if you get them often.
How to Choose the Best B2 Supplement for Migraines
When choosing a vitamin B2 supplement for migraines, keep these things in mind:
- Dosage:
- Most research suggests taking 400 mg of B2 daily to help prevent migraines, but the right dose for you may depend on the brand and your needs.
- Most over-the-counter riboflavin supplements contain between 100 mg and 400 mg per serving.
- Form:
- Vitamin B2 comes as capsules, tablets, soft gels, or liquids. Pick the type that fits best into your daily routine.
- Some people like liquids for faster absorption, while others choose tablets or capsules because they’re easy to take.
- Purity and Additives:
- Choose supplements without artificial additives, colors, or preservatives. Pure riboflavin or a good B-complex is best.
- Brand Reputation:
- Pick a trusted brand that clearly communicates its quality standards. Look for third-party testing or certifications to make sure the product is safe.
- Additional Ingredients:
- Some B2 supplements are part of a B-complex with other B vitamins. These can be helpful, but check the label so you don’t get too much of any one vitamin.
7 Best B2 Supplements for Migraines (2026 Updated)
Here are seven B2 supplements that may help reduce the frequency and severity of your migraines. This list is based on effectiveness, purity, user feedback, and quality.
| Product | Key Ingredients | Made In | Highlights | Form | Dose |
| 1. Thorne Research Riboflavin | Riboflavin, Rice Flour | USA | High bioavailability, trusted brand | Capsule | 400 mg |
| 2. Nature Made Vitamin B2 | Riboflavin | USA | Budget-friendly, easy to find in stores | Tablet | 100 mg |
| 3. Doctor’s Best High Potency Riboflavin | Riboflavin, Rice Powder | USA | Effective for migraine prevention | Capsule | 400 mg |
| 4. Solgar Vitamin B2 (Riboflavin) | Riboflavin | USA | Well-known, reliable brand, vegan-friendly | Capsule | 400 mg |
| 5. Jarrow Formulas Riboflavin | Riboflavin, Cellulose | USA | Great absorption, suitable for daily use | Capsule | 400 mg |
| 6. Pure Encapsulations Riboflavin | Riboflavin, Hypromellose | USA | Hypoallergenic, ideal for sensitive individuals | Capsule | 100 mg |
| 7. Life Extension Riboflavin | Riboflavin | USA | Combines high potency with optimal absorption | Capsule | 400 mg |
Detailed Product Reviews
Below you’ll find reviews of the seven best B2 supplements for migraines. Each review covers how well the product works, what’s in it, the form, dosage, and what users say. Use these details to help you choose the right supplement for your needs.
Thorne Research Riboflavin – Best for High Bioavailability
- Key Ingredients: Riboflavin, Rice Flour
- Made In: USA
- Form: Capsule
- Dose: 400 mg
Why We Recommend It:
Thorne Research Riboflavin is known for quality and is easy for your body to absorb. The 400 mg dose matches what studies suggest for migraine prevention.
Tester Feedback:
“I’ve been using Thorne’s Riboflavin for about two months, and my migraines have significantly decreased in frequency. I feel more energetic, and the few migraines Ihave had have been less intense. Definitely worth the investment if you struggle with migraines.”
Notes:
This supplement costs more than some others, but the quality is high. Take it with food to avoid stomach upset.
Nature Made Vitamin B2 – Best Budget Option
- Key Ingredients: Riboflavin
- Made In: USA
- Form: Tablet
- Dose: 100 mg
Why We Recommend It:
Nature Made Vitamin B2 is a good budget pick if you want to try riboflavin without spending much. The 100 mg dose is a lower option, which may work if you’re just starting out.
Tester Feedback:
“I’ve been using Nature Made B2 for a few weeks now, and while my migraines aren’t entirely gone, I have noticed fewer episodes. It’s a great option if you’re just starting to address your migraines and want something affordable.”
Notes:
This supplement may help with mild migraines, but it might not be strong enough if you need a higher dose. It’s free from artificial colors and preservatives.
Doctor’s Best High Potency Riboflavin – Best for Migraine Prevention
- Key Ingredients: Riboflavin, Rice Powder
- Made In: USA
- Form: Capsule
- Dose: 400 mg
Why We Recommend It:
Doctor’s Best offers a 400 mg riboflavin supplement at a good price. This high dose matches recommendations from studies for preventing migraines.
Tester Feedback:
“I have been using Doctor’s Best Riboflavin for migraine prevention for about a month, and it’s been fantastic! My migraines have become much less frequent, and the ones I do get aren’t as severe. I also have more energy throughout the day.”
Notes:
This is a strong supplement for migraine prevention, but you need to take it regularly. Take it with food if it bothers your stomach.
Solgar Vitamin B2 (Riboflavin) – Best for Vegan and Clean Labels
- Key Ingredients: Riboflavin
- Made In: USA
- Form: Capsule
- Dose: 400 mg
Why We Recommend It:
Solgar’s Vitamin B2 is vegan and free from artificial colors, flavors, and preservatives. Each capsule has 400 mg, which is a strong dose for migraine prevention.
Tester Feedback:
“I love that Solgar’s B2 is vegan-friendly and free from any unnecessary additives. I’ve been using it for a few weeks now, and my migraines have decreased. The product is easy to swallow, and I appreciate the transparency of the brand.”
Notes:
This is a good pick if you want a simple, vegan supplement. If you want more B vitamins, you may need a different product.
Jarrow Formulas Riboflavin – Best for Absorption and Daily Use
- Key Ingredients: Riboflavin, Cellulose
- Made In: USA
- Form: Capsule
- Dose: 400 mg
Why We Recommend It:
Jarrow Formulas Riboflavin is easy to absorb and comes in a 400 mg dose, which is what’s recommended for migraine prevention. The cellulose capsule is easy to digest.
Tester Feedback:
“Jarrow Formulas Riboflavin is the best I’ve tried. I’ve been dealing with chronic migraines for years, and this supplement has noticeably reduced their frequency. I feel more focused and less fatigued overall.”
Notes:
You may need to take this supplement for 2-3 months before seeing results. Take it with food if it upsets your stomach.
Pure Encapsulations Riboflavin – Best for Sensitive Individuals
- Key Ingredients: Riboflavin, Hypromellose
- Made In: USA
- Form: Capsule
- Dose: 100 mg
Why We Recommend It:
Pure Encapsulations is a good choice if you have allergies or a sensitive stomach. The 100 mg dose is gentle and works well if you’re new to riboflavin.
Tester Feedback:
“I have a sensitive stomach, so Pure Encapsulations is my go-to brand. I’ve been using their B2 supplement for a few weeks, and I’ve noticed fewer migraines. The capsules are easy on my digestive system, and I appreciate the quality.”
Notes:
If you need 400 mg for frequent migraines, this may not be enough. But it’s a good starting point if you want a lower dose.
Life Extension Riboflavin – Best for Long-Term Health Benefits
- Key Ingredients: Riboflavin
- Made In: USA
- Form: Capsule
- Dose: 400 mg
Why We Recommend It:
Life Extension Riboflavin offers a strong 400 mg dose for migraine prevention. It also supports your overall health and energy.
Tester Feedback:
“I started taking Life Extension Riboflavin to reduce my migraine frequency, and I’m amazed at the results. Not only has my migraine frequency decreased, but I also feel more energetic throughout the day.”
Notes:
Take this supplement regularly for the best results, and follow the recommended dose.
Conclusion: Choosing the Right Riboflavin Supplement for Migraines
Vitamin B2 can help reduce the frequency and severity of your migraines. If you want a strong option, try Thorne Research Riboflavin. If you’re on a budget, Nature Made Vitamin B2 is a good pick. For most people, 400 mg daily works best, and taking it regularly is important.
Talk to your doctor before starting any new supplement, especially if you take other medications or have health issues. The right riboflavin supplement may help you have fewer migraines and feel better overall.
This guide provides the details and advice you need to choose the best riboflavin supplement for migraines. Each review covers the pros, dosage, user feedback, and any downsides.
FAQ: Frequently Asked Questions
How much Vitamin B2 should I take for migraines?
Studies typically recommend 400 mg per day for migraine prevention.
Are there any side effects of riboflavin?
Riboflavin is water-soluble, so excess amounts are usually excreted in urine, making it safe for most people. However, taking excessive doses could cause gastrointestinal issues.
Can riboflavin work for everyone with migraines?
While many individuals benefit from riboflavin supplementation, it’s not a one-size-fits-all solution. Consult your healthcare provider for personalized advice.
How long does it take for riboflavin to reduce migraine frequency?
It may take 2-3 months of consistent use to see significant reductions in migraine frequency.
Can I combine riboflavin with other migraine treatments?
Yes, riboflavin can be taken alongside other treatments, such as over-the-counter pain relief, but be sure to discuss with your doctor.
References
- National Institutes of Health (NIH) – Office of Dietary Supplements.
- “Thiamine (Vitamin B1) and Riboflavin (Vitamin B2) Fact Sheet for Health Professionals.”
- U.S. Department of Health & Human Services, 2024.
- https://ods.od.nih.gov/factsheets/Riboflavin-HealthProfessional/
- Mayo Clinic.
- “Riboflavin (Vitamin B2) and Its Role in Health.”
- Mayo Clinic, 2024.
- https://www.mayoclinic.org
- Journal of Neurology, Neurosurgery, and Psychiatry.
- “Riboflavin in the Prevention of Migraine Attacks.”
- Journal of Neurology, Neurosurgery & Psychiatry, 2024.
- https://jnnp.bmj.com/content
- The Cochrane Database of Systematic Reviews.
- “Riboflavin for Preventing and Treating Migraines.”
- Cochrane Database of Systematic Reviews, 2024.
- https://www.cochranelibrary.com
- American Academy of Neurology.
- “Vitamin B2 (Riboflavin) for Migraine Prevention: Evidence and Recommendations.”
- American Academy of Neurology, 2024.
- https://www.aan.com
- The Journal of Clinical Nutrition.
- “The Role of Vitamin B2 in Migraines and Other Neurological Conditions.”
- The Journal of Clinical Nutrition, 2024.
- https://academic.oup.com
- National Headache Foundation.
- “The Use of Riboflavin in Migraine Treatment and Prevention.”
- National Headache Foundation, 2024.
- https://www.headaches.org
- PubMed Central (PMC).
- “The Effectiveness of Riboflavin in Reducing Migraine Frequency.”
- PubMed Central, 2024.
- https://pubmed.ncbi.nlm.nih.gov.