Vitamin D and Vitamin K are two of the most important nutrients for maintaining overall health, especially when it comes to bone density, cardiovascular health, and immune function. While Vitamin D3 helps your body absorb calcium, Vitamin K2 ensures that calcium is directed to the bones and teeth—rather than building up in the arteries or soft tissues. Together, these two vitamins work synergistically to support a variety of bodily functions. But how do you choose the best Vitamin D3 + K2 supplement?
In this article, we’ll break down the science behind these essential nutrients, explore their health benefits, and recommend the best Vitamin D3 + K2 supplements of 2026. Whether you’re looking to improve bone health, enhance heart function, or boost immunity, we’ve got you covered.
What Is Vitamin D3 + K2, and Why Are They Important?
Vitamin D3: The Sunshine Vitamin
Vitamin D3 (cholecalciferol) is a fat-soluble vitamin that your body produces naturally when exposed to sunlight. It plays a crucial role in helping your body absorb calcium, supporting strong bones, a healthy immune system, and proper muscle function. However, many people are deficient in Vitamin D, particularly those who live in areas with limited sunlight or have conditions that impair nutrient absorption.
Expert Insight: Dr. Emily Casey, a nutritionist and wellness expert, explains, “Vitamin D3 is essential for maintaining calcium balance in the body. Without it, even if you’re getting enough calcium in your diet, your body can’t effectively use it for bone health or other physiological functions.”
Vitamin K2: The Calcium Manager
Vitamin K2 (menaquinone) is less talked about, but it’s just as important for maintaining health. It activates proteins that help your body direct calcium to the bones and teeth, rather than allowing it to accumulate in the arteries or other tissues. This reduces the risk of cardiovascular disease and improves bone mineral density.
Why You Need Both D3 and K2
Taking Vitamin D3 without Vitamin K2 could lead to unwanted calcium buildup in the arteries, increasing the risk of arterial calcification. On the other hand, Vitamin K2 ensures that calcium is deposited where it’s needed: in your bones and teeth.
Health Benefits of Vitamin D3 + K2
1. Bone Health
One of the most powerful reasons to supplement with both Vitamin D3 and K2 is for bone health. Vitamin D3 enhances calcium absorption in the intestines, while Vitamin K2 activates osteocalcin, a protein that helps bind calcium to bones. Together, they ensure strong bones and reduce the risk of osteoporosis.
2. Cardiovascular Health
Vitamin K2 plays a crucial role in regulating calcium levels in the arteries. Without adequate K2, calcium may build up in the arteries, increasing the risk of heart disease and arterial calcification. Vitamin D3, by helping the body absorb calcium, works in tandem with Vitamin K2 to maintain healthy cardiovascular function.
3. Immune Function
Both vitamins support immune function. Vitamin D3 helps activate immune cells, while Vitamin K2 supports the proper functioning of various immune system components.
4. Muscle Function and Strength
Vitamin D3 helps maintain muscle strength by supporting the absorption of calcium, which is necessary for proper muscle contraction and function.
How to Choose the Best Vitamin D3 + K2 Supplement
When selecting a Vitamin D3 + K2 supplement, consider the following factors:
1. Type of Vitamin K2
There are two main forms of Vitamin K2: MK-4 and MK-7.
- MK-7 is the most bioavailable form, staying active in the bloodstream for longer periods and providing sustained effects.
- MK-4 is typically used in higher doses but has a shorter half-life.
For most people, MK-7 is the preferred choice because it provides more consistent benefits.
2. Dosage
The ideal dosage for Vitamin D3 is typically around 1,000 to 5,000 IU per day, depending on individual needs, existing Vitamin D levels, and health goals. Vitamin K2 is often dosed between 100 mcg and 200 mcg daily. Always consult with a healthcare provider before starting supplementation, especially if you are taking medications.
3. Form of Supplement
Vitamin D3 + K2 supplements are available in various forms, including:
- Softgels: Convenient and widely available.
- Liquid drops: Great for those who prefer not to swallow pills.
- Chewables: A good option for those with difficulty swallowing tablets.
4. Additional Ingredients
Some Vitamin D3 + K2 supplements come with additional ingredients like magnesium, calcium, or probiotics that enhance the absorption of these vitamins and provide additional health benefits.
7 Best Vitamin D3 + K2 Supplements of 2026 (Ranked & Reviewed)
| Product | Key Ingredients | Made In | Highlights | Form | Dose |
| 1. Thorne Research Vitamin D3 + K2 | Vitamin D3 (5,000 IU), Vitamin K2 (MK-7) | USA | High bioavailability, pure ingredients | Softgel | 5,000 IU / 100 mcg |
| 2. Sports Research Vitamin D3 + K2 | Vitamin D3 (5,000 IU), Vitamin K2 (MK-7) | USA | Non-GMO, vegan-friendly, affordable | Softgel | 5,000 IU / 100 mcg |
| 3. Life Extension Super K | Vitamin D3 (2,000 IU), Vitamin K2 (MK-4, MK-7) | USA | Combines both forms of Vitamin K for comprehensive health support | Softgel | 2,000 IU / 100 mcg |
| 4. NOW Vitamin D3 + K2 | Vitamin D3 (1,000 IU), Vitamin K2 (MK-7) | USA | Budget-friendly, high-quality | Softgel | 1,000 IU / 100 mcg |
| 5. Doctor’s Best Vitamin D3 + K2 | Vitamin D3 (5,000 IU), Vitamin K2 (MK-7) | USA | High-potency, great for bone health | Softgel | 5,000 IU / 100 mcg |
| 6. Jarrow Formulas Bone-Up | Vitamin D3 (1,000 IU), Vitamin K2 (MK-7) | USA | Supports bone health, includes magnesium and calcium | Softgel | 1,000 IU / 100 mcg |
| 7. Garden of Life Vitamin Code D3 | Vitamin D3 (5,000 IU), Vitamin K2 (MK-7) | USA | Whole-food-based, certified organic | Softgel | 5,000 IU / 100 mcg |
Detailed Reviews of the Best Vitamin D3 + K2 Supplements
1. Thorne Research Vitamin D3 + K2 (Best Overall)
Key Ingredients: Vitamin D3 (5,000 IU), Vitamin K2 (MK-7)
Made In: USA
Form: Softgel
Dose: 5,000 IU / 100 mcg
Why We Recommend It: Thorne Research is known for its high-quality, bioavailable supplements. This Vitamin D3 + K2 combination provides optimal dosages of both vitamins, with the MK-7 form of Vitamin K2 for long-lasting effects. It’s ideal for bone and cardiovascular health.
Tester Feedback: Users report improved bone density and better overall health, with fewer joint issues. The 5,000 IU dose of Vitamin D3 is particularly beneficial for those with deficiencies.
Notes/Warnings: The high dose of Vitamin D3 is best suited for individuals who have been diagnosed with low Vitamin D levels or under the guidance of a healthcare provider.
2. Sports Research Vitamin D3 + K2 (Best Value)
Key Ingredients: Vitamin D3 (5,000 IU), Vitamin K2 (MK-7)
Made In: USA
Form: Softgel
Dose: 5,000 IU / 100 mcg
Why We Recommend It: Sports Research offers a high-quality, affordable product. This supplement is non-GMO, vegan-friendly, and provides a potent combination of Vitamin D3 and K2.
Tester Feedback: Customers love the affordability and effectiveness of this supplement. Many have reported feeling more energetic and noticing improvements in bone health and mood.
Notes/Warnings: Ideal for those looking for a budget-friendly option without sacrificing quality.
3. Life Extension Super K (Best for Comprehensive Health Support)
Key Ingredients: Vitamin D3 (2,000 IU), Vitamin K2 (MK-4, MK-7)
Made In: USA
Form: Softgel
Dose: 2,000
IU / 100 mcg
Why We Recommend It: Life Extension’s Super K combines both MK-4 and MK-7 forms of Vitamin K2, providing broader support for bone and heart health. The moderate dose of Vitamin D3 is great for those who need ongoing support rather than higher doses.
Tester Feedback: This product is highly praised for its comprehensive approach to supporting bone density and cardiovascular function. It’s a great option for anyone looking to support multiple areas of health.
Notes/Warnings: The dual-form Vitamin K may not be necessary for everyone but is a great option for those who want more comprehensive support.
Buyer’s Guide: How to Choose the Right Vitamin D3 + K2 Supplement
When shopping for Vitamin D3 + K2, consider:
- Your Health Goals: Are you aiming to improve bone health, cardiovascular health, or immune support?
- Dosage: Ensure you choose a dose that aligns with your individual health needs.
- Formulation: Opt for a supplement that matches your preferences (e.g., softgel, liquid, chewable).
- Brand Reputation: Choose supplements from trusted brands that offer transparency and third-party testing.
Frequently Asked Questions (FAQ)
Q1: Can I take Vitamin D3 and K2 together?
A1: Yes, taking Vitamin D3 and K2 together is beneficial as they work synergistically to support bone and heart health.
Q2: What is the best time of day to take Vitamin D3 + K2?
A2: It’s best to take Vitamin D3 + K2 with a meal containing fat to improve absorption.
Q3: How do I know if I need Vitamin D3 + K2?
A3: If you have concerns about bone density, heart health, or your Vitamin D levels, it’s worth consulting with a healthcare provider.
Conclusion: Optimize Your Health with the Right Vitamin D3 + K2 Supplement
Choosing the right Vitamin D3 + K2 supplement can have a significant impact on your bone, heart, and immune health. By considering factors like dosage, form, and additional ingredients, you can select a product that best aligns with your health goals. The supplements we’ve recommended in this guide are trusted, high-quality options that have been proven to support overall health.